The term head and neck

The term head and neck cancer refers to a group of biologically similar cancers originating from the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx. Most head and neck cancers are squamous cell carcinomas (SCCHN), originating from the mucosal lining (epithelium) of these regions.[1] Head and neck cancers often spread to the lymph nodes of the neck, and this is often the first (and sometimes only) manifestation of the disease at the time of diagnosis. Head and neck cancer is strongly associated with certain environmental and lifestyle risk factors, including tobacco smoking, alcohol consumption, UV light and occupational exposures, and certain strains of viruses, such as the sexually transmitted human papillomavirus.[2]Football Flags
elektronine parduotuve pigu

The ERM protein family consists of three closely-related proteins, ezrin,[2] radixin[3] and moesin.[4][5] The three paralogs, ezrin, radixin and moesin, are present in vertebrates whereas other species have only one ERM gene. Therefore, in vertebrates these paralogs likely arose by gene duplication.[6]
ERM proteins are highly conserved throughout evolution . More than 75% identity is observed in the N-terminal and the C-terminal of vertebrates (ezrin, radixin, moesin), Drosophila (dmoesin) and C. elegans (ERM-1) homologues.[7]


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